Herpes simplex - Herpes Rọrunhttps://en.wikipedia.org/wiki/Herpes_simplex
Herpes Rọrun (Herpes simplex) jẹ akoran ọlọjẹ (ọlọjẹ Herpes). Awọn akoran ti wa ni tito lẹtọ da lori apakan ti ara ti o ni akoran. Herpes ẹnu jẹ arun ti o wọpọ ati pe o kan oju tabi ẹnu. O le ja si awọn roro kekere ni awọn ẹgbẹ ti a npe ni ọgbẹ tutu tabi awọn roro iba. Herpes abe, ti a mọ nirọrun bi Herpes, le ni awọn aami aiṣan kekere tabi awọn roro ti o ṣii ti o si ja si awọn ọgbẹ kekere. Iwọnyi nigbagbogbo larada ni ọsẹ meji si mẹrin. Awọn irora tingling le waye ṣaaju ki awọn roro han. Iṣẹlẹ akọkọ jẹ igba pupọ diẹ sii ati pe o le ni nkan ṣe pẹlu iba, irora iṣan, awọn apa ọgbẹ ti o wú ati awọn efori. Awọn rudurudu miiran ti o fa nipasẹ ọlọjẹ Herpes pẹlu: herpetic whitlow nigbati o kan awọn ika ọwọ, Herpes ti oju, ati Herpes tuntun nigbati o kan ọmọ tuntun.

Awọn oriṣi meji ti ọlọjẹ herpes rọrun (herpes simplex) , iru 1 (HSV-1) ati iru 2 (HSV-2). HSV-1 diẹ sii maa n fa awọn akoran ni ayika ẹnu nigba ti HSV-2 diẹ sii maa n fa awọn akoran abẹ-ara. Wọn tan kaakiri nipasẹ olubasọrọ taara pẹlu ẹni ti o ni akoran. Abe Herpes ti wa ni classified bi a ibalopọ zqwq ikolu. O le tan si ọmọ ikoko nigba ibimọ. Lẹhin ikolu, awọn ọlọjẹ naa ni a gbe lọ pẹlu awọn ara ifarako si awọn ara sẹẹli nafu, nibiti wọn ngbe ni igbesi aye. Awọn okunfa ti iṣipopada le pẹlu: idinku iṣẹ ajẹsara, aapọn, ati ifihan ti oorun.

Ni ọpọlọpọ awọn ọran, awọn oogun antiviral ni a mu nikan nigbati awọn ami aisan ba le. Oogun antiviral lojoojumọ le jẹ ogun fun ẹnikan ti o ni akoran loorekoore. Ko si ajesara to wa ati ajesara shingles ko ṣe idiwọ Herpes simplex. Awọn itọju pẹlu oogun apakokoro bi aciclovir tabi valaciclovir le dinku biba awọn aami aisan naa.

Awọn oṣuwọn agbaye ti boya HSV-1 tabi HSV-2 wa laarin 60% ati 95% ninu awọn agbalagba. HSV-1 maa n ni akoran lakoko igba ewe. Awọn eniyan miliọnu 536 ni agbaye (16% ti olugbe) ti ni akoran pẹlu HSV-2 bi ti 2003 pẹlu awọn iwọn nla laarin awọn obinrin ati awọn ti o wa ni agbaye to sese ndagbasoke. Pupọ eniyan ti o ni HSV-2 ko mọ pe wọn ti ni akoran.

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  • Herpes simplex lori aaye.
  • Herpes Rọrun (Herpes simplex) ― Herpes simplex ikolu ninu awọn ika ọwọ jẹ wọpọ ni awọn ọmọde ju ti awọn agbalagba lọ.
  • Ti awọn aami aisan ba le, gbigba oogun antiviral jẹ iranlọwọ julọ ni idinku awọn aami aisan.
  • Ti o ba waye ni ayika ẹnu, angular cheilitis yẹ ki o jẹ iyatọ. Sibẹsibẹ, ni aworan yii, o ṣee ṣe diẹ sii lati jẹ Herpes bi ọpọlọpọ awọn roro kekere wa ni ayika ẹnu.
  • Herpes gingiva ― Awọn akoran Herpes le waye kii ṣe ni ayika ẹnu nikan, ṣugbọn tun ni inu inu, perinasal, ati awọn agbegbe periocular.
  • Herpes abe ninu awọn obirin.
  • Herpes lori awọn buttocks jẹ ijuwe nipasẹ ifasẹyin nigbati o rẹ.
  • Ni awọn iṣẹlẹ ti ikolu ni ibigbogbo, itọju aladanla le nilo, bii pẹlu zoster herpes.
References Herpes Simplex Type 1 29489260 
NIH
Ikolu HSV-1 nlọsiwaju nipasẹ ikolu akọkọ ti awọn sẹẹli epithelial, ti o tẹle pẹlu lairi, ni pato ninu awọn neurons, ati atunṣe. HSV-1 ti o wọpọ nfa ibẹrẹ ati awọn eruptions vesicular loorekoore, nipataki lori ẹnu ati mucosa abe. Awọn ifihan rẹ wa lati awọn Herpes orolabial si ọpọlọpọ awọn ipo bii herpetic folliculitis, awọn akoran awọ ara, ilowosi oju, ati awọn ọran ti o nira bi Herpes encephalitis. Itọju ọlọjẹ n ṣe iranlọwọ lati ṣakoso ikolu HSV.
Herpes simplex virus type 1 (HSV-1) is a member of the Alphaherpesviridae subfamily. Its structure is composed of linear dsDNA, an icosahedral capsid that is 100 to 110 nm in diameter, with a spikey envelope. In general, the pathogenesis of HSV-1 infection follows a cycle of primary infection of epithelial cells, latency primarily in neurons, and reactivation. HSV-1 is responsible for establishing primary and recurrent vesicular eruptions, primarily in the orolabial and genital mucosa. HSV-1 infection has a wide variety of presentations, including orolabial herpes, herpetic sycosis (HSV folliculitis), herpes gladiatorum, herpetic whitlow, ocular HSV infection, herpes encephalitis, Kaposi varicelliform eruption (eczema herpeticum), and severe or chronic HSV infection. Antiviral therapy limits the course of HSV infection.
 Herpes Simplex Type 2 32119314 
NIH
Herpes simplex virus type 2 (HSV-2) jẹ akoran ti o tan kaakiri, ti o kan ni ayika 22% ti awọn agbalagba ti ọjọ-ori 12 ati loke, lapapọ 45 awọn agbalagba ni Amẹrika. Lakoko ti HSV-1 maa n fa awọn egbò ẹnu, o tun le ja si awọn egbo abe. Sibẹsibẹ, nigbati awọn alaisan ba ni awọn ọgbẹ abẹ-ara, HSV-2 nigbagbogbo jẹ ibakcdun akọkọ. Awọn aami aiṣan ti awọn ibesile HSV-2 nigbagbogbo jẹ aiduro, bii irẹjẹ abo ati irritation, eyiti o le ṣe idaduro iwadii aisan ati itọju. Idaduro yii le ja si gbigbe siwaju si awọn eniyan ti ko ni akoran.
Herpes simplex virus type 2 (HSV-2) continues to be a common infection, affecting approximately 22% of adults ages 12 and older, representing 45 million adults in the United States alone. While HSV-1 often affects the perioral region and can be known to cause genital lesions, HSV-2 is more commonly the consideration when patients present with genital lesions. Despite this, most outbreaks of the infection will present with nonspecific symptoms such as genital itching, irritation, and excoriations, which may cause diagnosis and treatment to be delayed. As a result, further exposure to uninfected individuals may occur.
 Prevention and Treatment of Neonatal Herpes Simplex Virus Infection 32044154 
NIH
Herpes simplex virus (HSV) nigbagbogbo nfa awọn akoran bii Herpes abe ati ọgbẹ tutu ni awọn ọdọ ati awọn agbalagba. Nigbati HSV ba npa ọmọ ikoko laarin ọsẹ 4-6 akọkọ ti igbesi aye, o le ja si aisan ti o lagbara pẹlu awọn abajade to ṣe pataki. Ni kiakia ṣe iwadii aisan HSV ọmọ tuntun jẹ pataki lati da arun na duro lati buru si, idilọwọ awọn ọran ti iṣan (paapaa iku) .
Herpes simplex virus (HSV), a member of the Herpesviridae family, is a well-known cause of infections including genital herpes and herpes labialis in the adolescent and adult population. Transmission of HSV infection to an infant during the first 4-6 weeks of life can lead to devastating disease with the potential for poor outcomes. Early diagnosis is imperative when evaluating neonatal HSV infection in order to prevent further disease progression, neurological complications, and even death.
 Herpes simplex virus infection in pregnancy 22566740 
NIH
Herpes simplex ikolu jẹ eyiti o wọpọ ati pe o le gba lati ọdọ awọn aboyun si awọn ọmọ wọn. Kokoro yii le fa awọn ọran ilera to ṣe pataki tabi paapaa iku ninu awọn ọmọ tuntun. Lakoko ti o jẹ toje lakoko oyun funrararẹ, o maa n ṣẹlẹ lakoko ibimọ. Ewu ti o ga julọ ti iya ba ni akoran ni awọn ipele nigbamii ti oyun. Sibẹsibẹ, ewu yii le dinku nipasẹ lilo awọn oogun antiviral tabi jijade fun apakan C ni awọn ipo kan.
Infection with herpes simplex is one of the most common sexually transmitted infections. Because the infection is common in women of reproductive age it can be contracted and transmitted to the fetus during pregnancy and the newborn. Herpes simplex virus is an important cause of neonatal infection, which can lead to death or long-term disabilities. Rarely in the uterus, it occurs frequently during the transmission delivery. The greatest risk of transmission to the fetus and the newborn occurs in case of an initial maternal infection contracted in the second half of pregnancy. The risk of transmission of maternal-fetal-neonatal herpes simplex can be decreased by performing a treatment with antiviral drugs or resorting to a caesarean section in some specific cases.
 Clinical management of herpes simplex virus infections: past, present, and future 30443341 
NIH
Herpes simplex virus (HSV) orisi 1 ati 2 akoran ọpọlọpọ awọn eniyan ni agbaye. Nigbagbogbo, ọlọjẹ naa dakẹ ninu awọn sẹẹli nafu lẹhin ti o ba awọ ara jẹ, ṣugbọn o le tun mu ṣiṣẹ nigbamii, nfa awọn ọgbẹ tutu. Nigbakuran, o nyorisi awọn iṣoro to lagbara bi awọn akoran oju, igbona ọpọlọ, tabi awọn ipo ti o lewu ninu awọn ọmọ ikoko ati awọn eniyan ti o ni awọn eto ajẹsara alailagbara. Lakoko ti awọn oogun lọwọlọwọ ṣe iranlọwọ lati ṣakoso awọn akoran, eewu resistance oogun ati awọn ipa ẹgbẹ jẹ ibakcdun kan. A nilo awọn oogun tuntun lati dojukọ ọlọjẹ naa dara julọ.
Infection with herpes simplex virus (HSV) types 1 and 2 is ubiquitous in the human population. Most commonly, virus replication is limited to the epithelia and establishes latency in enervating sensory neurons, reactivating periodically to produce localized recurrent lesions. However, these viruses can also cause severe disease such as recurrent keratitis leading potentially to blindness, as well as encephalitis, and systemic disease in neonates and immunocompromised patients. Although antiviral therapy has allowed continual and substantial improvement in the management of both primary and recurrent infections, resistance to currently available drugs and long-term toxicity pose a current and future threat that should be addressed through the development of new antiviral compounds directed against new targets.